The phone started ringing before there was a website. At first, most of the calls were from people struggling with addiction. They had heard that ibogaine could be a powerful tool for detox and recovery, and they wanted to know if Barry could help guide them through the process. He spent hours on the phone explaining what ibogaine was, how it worked, what treatment involved, and what people could realistically expect. This was around 2008, when almost nothing had been written publicly about ibogaine and reliable information was difficult to find. As more calls came in, Barry eventually created a website so he would not have to repeat the same long explanations over and over. That website became the beginning of IbogaQuest.
Barry had known about ibogaine since the late 1960s, through a mutual friend who introduced him to Howard Lotsof himself. Lotsof was the man who first documented ibogaine's anti-addictive properties, and Barry was in his orbit years before ibogaine became a subject of scientific or clinical interest. His own first flood dose came in 2000. He was already living in Mexico when the calls started. He wasn't looking to run a clinic. He was just the person who picked up.
- Founded by Barry Rossinoff, who had a direct personal relationship with Howard Lotsof, the person most responsible for documenting ibogaine's anti-addictive properties.
- Standard 7-day program: flood dose Tuesday and Wednesday, booster dose (two-thirds the size) on Friday. After years of refining different treatment approaches, IbogaQuest found that offering a second ibogaine dose later in the week produced the most beneficial overall results.
- Aftercare continues via integration sessions and direct WhatsApp contact. The cohort is small enough that patients form genuine connections with each other and team members. Program fee includes private accommodation, meals, ground transport from Mexico City, and all therapeutic modalities.
Who I Spoke With
Barry shared the deeper history behind IbogaQuest as well as the details of the clinic's evolving protocols. He spoke about knowing Howard Lotsof personally, about how the treatment landscape has changed from heroin to fentanyl, 7-OH kratom, and other new substances now on the market. And about why IbogaQuest has intentionally remained small for the past seventeen years. He's thoughtful and precise, the kind of person who has spent decades around this medicine and speaks about it without exaggeration.
Nienke Berkenbosch, one of the team's facilitators, described what the experience actually feels like from the inside. She spoke about the rhythm of the week, the importance of preparation and integration, the atmosphere the team tries to create, and why keeping the groups small allows patients to receive deeper attention and support throughout their process.
"It's almost like a boutique situation. We're not motivated by becoming larger. We want to continue becoming better and going deeper in the work. By treating only seven patients per month, we're able to give careful attention to each individual person and each unique process, from the preparation before arrival to the aftercare and integration that follows treatment."Barry Rossinoff, Founder, IbogaQuest
That has not changed since 2009, and it is not changing.
Who They Treat
About a third of IbogaQuest's patients come for addiction treatment, whether to substances or deeply rooted habitual patterns. The other two-thirds are a mix: PTSD, traumatic brain injury, depression, and what the team calls psychospiritual work. That last category is people who aren't in crisis exactly, but who want to make a fundamental change, or are seeking a rite of passage, and have decided ibogaine is how they want to do it.
The patient mix skews roughly 60 to 70 percent men, though that has been shifting. The clinic recently added an all-women's retreat offered a couple of times a year, focused exclusively on psychospiritual work in an all-female container. The standard monthly sessions continue to include women coming for all reasons, including addiction.
One thing hasn't shifted: IbogaQuest requires genuine self-motivation. If someone is coming because a family member is paying or pushing, the team is already hesitant.
How They Run Treatment
Medical Screening
Before any deposit is accepted, applicants fill out an online form covering their psychological and medical history. A team member follows up by phone or video to assess fit. Once a deposit is placed to hold a date, preparation formally begins.
Applicants are required to submit a panel of medical tests before arrival. The clinical team reviews the results and must approve before anyone travels. The required panel is:
- Blood pressure reading
- EKG (including the graph)
- Complete Blood Count (CBC)
- Basic Metabolic Panel
- General urinalysis
- Liver function test
Patients over 60, or with specific medical conditions, may be required to add a heart stress test. If the screening turns up a disqualifier, the deposit is refunded.
The Medicine
IbogaQuest uses ibogaine HCl for addiction interruption work. The HCl is sourced from a lab that provides a certificate of analysis covering the full chain, from plant extraction to alkaloid purity. The reason they use HCl specifically: it is the most studied of the iboga alkaloids and the one with the clearest evidence for the addiction interruption effect. With organic preparations like purified total alkaloid (PTA), total alkaloid (TA), or root bark, the exact milligram-per-kilogram dose is harder to quantify, and the team needs to be sure they are hitting a specific saturation in the brain to produce what is called the "reset" effect.
For psychospiritual programs, or when a patient familiar with the plant requests it, the clinic will use a total alkaloid preparation. TA carries more of the supporting alkaloids and, for some people, produces an experience closer to the full-plant experience than isolated HCl. But it is not used for addiction interruption.
The flood dose is calibrated to each patient based on body weight, substance use history, current health conditions, mental and emotional readiness, and how the medicine appears to be working as the session unfolds.
Monitoring and Emergency Protocol
During every medicine intake session, the space is staffed by a physician, a nurse, and two paramedics. A fully equipped ambulance is on site. Blood pressure and pulse oximetry are monitored continuously. A cardiac monitor is used where clinically indicated, and a defibrillator is available on site.
The nearest hospital is about 20 minutes from the property. Transfer would be handled by the on-site ambulance team.
Over 17 years of operation, IbogaQuest has had to use the ambulance once. That call followed a patient who had given incomplete information about their substance use on the intake form, and the response led directly to stricter intake screening and drug testing. Nienke's framing of the safety philosophy: "Our strongest safety measures are preventative. Thorough medical screening, careful preparation, and precise dosing protocols." Roughly 1,300 patients over 17 years, one ambulance call. That is a strong record, particularly given ibogaine's cardiovascular risk profile.
The Seven-Day Program
The week has a deliberate rhythm. Each element follows from the one before it.
The Friday booster deserves a direct explanation, because IbogaQuest arrived at it by trying the alternative first.
"We've experimented with various elements over the years. Our outcomes illustrate that having a second dose of ibogaine is much more effective than using any other substance."Barry Rossinoff, IbogaQuest
This is not an ideological position. Their patient outcomes were better with a second ibogaine dose on Friday than with anything else they tested as an adjunct. Barry said the results have been universally positive: the booster consistently helps patients integrate what surfaced during the flood, and it extends the depth of the experience rather than shifting the direction of it.
The team's position is also specific to the treatment week. After the week ends, patients are free to explore other medicines on their own; IbogaQuest does not take a stance on that one way or the other. During the seven days they are running, however, the protocol is ibogaine only.
The program is structured but not rigid. Patients are invited to participate in whatever feels right for them. "We want people to be comfortable and safe," Nienke said. "Most of the time, people really enjoy the flow of the week."
The Noribogaine Window
Noribogaine, ibogaine's primary metabolite, remains pharmacologically active in the body for roughly two to three months after a flood dose. This is the noribogaine window. It is where the actual behavioral work either consolidates or doesn't. The flood itself is the catalyst. What happens in the weeks that follow is the treatment.
IbogaQuest is direct with patients about this: a successful flood is not the same thing as a successful treatment. The team encourages active integration through the window, staying in contact with the integration team, working with a therapist at home, and avoiding the temptation to declare the work finished when the visions end.